DSC00590  基本信息

  名:  张晓丽

  别: 

  出生日期:  1961.11

  称:  教授

  研究类别: 分析化学

  工作单位: 分析化学研究所

  话: 15954101588

  真: 0531-88561318

  E-mail zhangxl@sdu.edu.cn

工作学习经历】

1986~至今:  山东大学化学与化工学院任教  现职称: 教授

1983~1986:  山东大学化学系  研究生  导师王树仁教授

1979~1983:  山东大学化学系  本科生       

 

【讲授的主要课程】

1.分析化学               本科生基础课

2.分析化学实验技术       研究生学位课

3.现代光电分析(电化学)研究生学位课

4.生命科学中的电分析     研究生专业选修课

 

【承担的实践性教学】

 1.基础化学实验          本科生基础课

 2.无机及分析化学实验    本科生基础课

 3.仪器分析实验          本科生基础课

 

【教学研究课题】

1. 教育部标准化实验室建设,9800年,负责人之一。

2. 山东大学重点实验室中级仪器实验室建设,0002年,负责人。

3. 基础化学实验多媒体教学课件制作(校内),0001年负责人之一。

4. 基础化学实验试题库的建立,山东大学,0002年,第1名。

5. 基础化学实验课教学模式的创新实践,山东大学,0002年,第2名。

6. 山东省高校化学实验新体系立体化系列教材建设,省教育厅,0306年,参加者

7. 教育部高等学校化学素材库建设,0406,参加者

【获得的教学表彰/奖励】

1.《基础化学实验》山东大学出版社,山东大学优秀教材一等奖,2002年,主编之一

2. 基础化学实验课程体系和教学模式创新与实践 山东大学优秀教学成果一等奖,2000 年, 2位。

3. 无机及分析化学实验课程体系与内容的革新教材和CAI课件 山东省教育厅省级教学成果三等奖,2001年,2位。

4. 基础化学实验多媒体教学课件 山东大学优秀教学成果二等奖,2001年,第3位。

【科研方向】

1.电化学传感界面及环境污染物的检测

2电化学-表面增强拉曼光谱联用技术

3.细胞-酶生物电化学传感器

4.扫描电化学显微术单细胞分析

【研究课题】

主持:

1.  国家自然科学基金 电化学发光共振能量转移技术及应用 2010.1- 2012.12

2.  国家自然科学基金 扫描电化学显微术单细胞分析2007.1- 2009.12

3.  省自然科学基金 基于分子自组装技术的压电生物传感器2000.1- 2002.12  

4.  省自然科学基金 单分子及活细胞表面酶的纳米分辨的SECM成像,2004.1- 2006.12 

5.  省自然科学基金 基于微纳米球介导酶联技术DNA单分子电化学检测  2009.1-2011.12

6.  中科院长春应化所,生物物质的扫描电化学显微镜成像及定量测定,2005.1 -2006.12

参加: 

1.     国家自然科学基金重点项目 单细胞分析化学方法研究,2003.1-2006.12

2.     国家自然科学基金 非石英晶体压电传感检测研究 2003.1-2005.12

3.     国家自然科学基金 压电传感器应用于超薄分子膜特性的研究 1996.1-1998.12

【学术论文】

 

1.         Xiaofei Hu, Rongyue Wang, Yi Ding, Xiaoli Zhang*, Wenrui Jin, Electrochemiluminescence of CdTe quantum dots as labels at nanoporous gold leaf electrode for ultrasensitive DNA analysis, Talanta, 80 (2010) 1737-1743

2.         Ultrasensitive electrogenerated chemiluminescence immunoassay by magnetic nanobead amplification, Electroanalysis, 22 (2010) 333-337

3.         Single-molecule-counting protein microarray with nanoliter samples and its application in the dynamic protein expression of living cells, Biosen & Bioelectron.,26 (2011) 3688-3691

4.         Electrochemiluminescence immunoassay at a nanoporous gold leaf electrode and using CdTe quantum dots as labels, Microchem. Acta, 172 (2011) 285-290

5.         Electrochemical simultaneous determination of nitrophenol isomers at nano-gold modified glassy carbon electrode, J.Appl.Electrochem., 41 (2011) 687-694

6.         Determination of dopamine with improved sensitivity by exploiting an accumulation effect at a nano-gold electrode modified with poly(sulfosalicylic acid), Microchem. Acta, 174 (2011) 345-352

7.         Electrochemiluminescence resonance energy transfer between an emitter electrochemically generated by luminol as the donor and luminescent quantum dots as the acceptor and its biological application, Chem.Commun., 47 (2011) 8292-8294

8.         Strong anodic near-infrared electrochemiluminescence from CdTe quantum dots at low oxidation potentials, Chem.Commun.,47 (2011) 10115-10117

9.         Electrochemiluminescence DNA sensor based on hairpin structure DNA as recognition element and Ru(bpy)32+-doped silica nanoparticles as signal-producing compound, Electroanalysis, 23 (2011) 2693-2698

10.     DNA microspot assay using sigle-molecule detection and requiring 1.8nL samples only, Microchem. Acta, 174 (2011) 201-206

11.     Electrochemiluminescence resonance energy transfer between quantum dots (QDs) as the donor and Cy5 dye molecules as the acceptor in QD-Cy5 conjugates with biomolecules as the linker, Electrochemistry Communications, 13 (2011) 1174-1177

12.     Ultrasensitive electrochemiluminescence method for determination of DNA using Ru(bpy)32+-coated magnetic submicrobeads wrapped with carbon nanotubes, Electrochem.Commun., 13 (2011) 1499-1501

13.     Fabrication of nano-porous hydroxyapatite modified electrode and its application for determination of p-chlorophenol, J.Nanosci.&Nanotech.,  11 (2011) 1-8

14.     Electrochemical detection of chloride at the multilayer nano-silver modified indium-tin oxide thin electrodes, J.Electroanal.Chem., 665 (2012) 26-3l

15.     Electrochemiluminescence DNA Sensor Based on Ru(bpy)32+-Doped Silica Nanoparticles Labeling and Proximity-Dependent Surface Hybridization Assay, Journal of Solid State Electrochemistry, 16 (2012) 247-252

16.     Liping Shen, Yuming Sun, Jun Li, Li Chen, Lu Li, Guizheng Zou,* Xiaoli Zhang*, Wenrui Jin, Heterogeneous electrochemiluminescence spectrometry of Ru(bpy)32+ for determination of trace DNA  and its application in measurement of gene expression level, Talanta, 89 (2012)427-432

17.     Electrochemical sensor for epinephrine based on a glassy carbon electrode modified with graphene/gold nanocomposites, J.Electroanal.Chem., 669 (2012) 35-41

18.     Electrodeposition of CdSe quantum dots and its application to an electrochemiluminescence immunoassay for α-fetoprotein, Microchemica Acta, 178 (2012) 323-330

19.     Electrogenerated Chemiluminescence Sensor for Formaldehyde Based on Ru(bpy)32+-Doped Silica Nanoparticles Modified Au Electrode, Materiasl Science & Engineering C, 32 (2012) 2169-2174

20.     Measuring interactions and conformational changes of dna molecules using electrochemiluminescence resonance energy transfer in the conjugates consisting of luminol, dna and quantum dot, Electrochimica Acta, 80 (2012) 171-179

21.     Nanocomposite of graphene based sensor for paraquat: synergetic effect of nano-gold and ionic liquids on electrocatalysis, Analytical Methods, 4 (2012) 3974-3980

22.     Nanocomposite of electrochemically reduced graphene oxide and gold nanoparticles enhanced electrochemilunescence of peroxydisulfate and its immunosensing abililty towards human IgG, J.Electroanal.Chem., 686 (2012) 25-31

23.     Signal amplification based on DNA hybridization-dehybridization reaction on the surface of magnet submicrobeads for ultrasensitive DNA detection, Analyst,137(2012),4849- 4854

24.     Electrodeposited apatite coating for solid-phase microextraction and sensitive indirect voltammetric determination of fluoride ions, Talanta, 115 (2013) 500-505

25.     Electrochemical co-reduction synthesis of graphene/nano-goldcomposites and its application to electrochemical glucose biosensor, Electrochimica Acta, 112 (2013) 774-782

26.     Electrogenerated chemiluminescence sensor for glutathione with Ru(bpy)32+-doped silica nanoparticles, Journal of Solid State Electrochemistry, 17 (2013) 795-803

27.     Applications of electrochemiluminescence resonance energy transfer between CdSe/ZnS quantum dots and cyanine dye (Cy5) molecules in evaluating interactions and conformational changes of DNA molecules, Electrochimica Acta, 94 (2013) 367-373

28.     A method based on electrodeposition of reduced graphene oxide on glassy carbon electrode for sensitive detection of theophylline, Journal of Solid StateElectrochemistry, 17 (2013) 167-173

29.     Non-enzymatic glucose biosensor based on copper oxide-reduced grapheme oxide nanocomposites synthesized from water-isopropanol solution, Electrochimica Acta, 130 (2014)  253-260